Awarded Grants
Awarded Grants
Defining ciliary signaling and targets in CDKL5 Deficiency Disorder
Peter K. Jackson, PhD
Stanford University School of Medicine
$150,000
Awardee: Peter K. Jackson, PhD
Institution: Stanford University School of Medicine
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Impact of Cdkl5 deficiency on cortical dynamics and network architecture
Michael J. Higley, MD, PhD
Yale University
$150,000
Awardee: Michael J. Higley, MD, PhD
Institution: Yale University
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Systems Analysis of the CDKL5-Deficiency Disorder (CDKL5-DD) Cerebrospinal Fluid Proteome
Victor Faundez, MD, PhD
Emory University
$150,000
Awardee: Victor Faundez, MD, PhD
Institution: Emory University
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Characterization and correction of Cdkl5 nuclear function in human CDD neurons during maturation
Simone DiGiovanni, MD, PhD
Imperial College London
$149,277
Awardee: Simone DiGiovanni, MD, PhD
Institution: Imperial College London
Award Amount: $149,277
Elucidate the neural mechanisms underlying sleep disturbances and the relation between seizures and sleep-wake cycle in CDKL5 deficiency disorder (CDD)
Liqin Cao, PhD
Tsukuba University
$139,940
Awardee: Liqin Cao, PhD
Institution: Tsukuba University
Award Amount: $139,940
Visualizing the effect of CDKL5 deficiency on ciliary core structures
Alan Brown, PhD
Harvard Medical School
$150,000
Awardee: Alan Brown, PhD
Institution: Harvard Medical School
Award Amount: $150,000
Incorporation of functional unnatural amino acids into CDKL5 to study its function in cells
Maolin Guo, PhD
University of Massachusetts, Dartmouth
$150,000
Awardee: Maolin Guo, PhD
Institution: University of Massachusetts, Dartmouth
Award Amount: $150,000
Ascertaining the cell-autonomous effects of CDKL5 mutations in every brain cell type
Steven A. McCarroll, PhD
Harvard Medical School
$140,000
Awardee: Steven A. McCarroll, PhD
Institution: Harvard Medical School
Award Amount: $140,000
Assessing peripheral sensory neuron dysfunction in animal models for CDKL5 deficiency disorder
Lauren Orefice, PhD
Massachusetts General Hospital
$150,000
Awardee: Lauren Orefice, PhD
Institution: Massachusetts General Hospital
Award Amount: $150,000
CDKL5 regulation of ciliary assembly and signaling
Gregory J. Pazour, PhD
University of Massachusetts Medical School
$150,000
Awardee: Gregory J. Pazour, PhD
Institution: University of Massachusetts Medical School
Award Amount: $150,000
Structural/functional characterization of full-length hCDKL5 isoform 1 produced in recombinant marine bacteria and use of pharmacological chaperones to stabilize hCDKL5 missense mutants
Maria Luisa Tutino, PhD
University of Naples
$148,300
Awardee: Maria Luisa Tutino, PhD
Institution: University of Naples
Award Amount: $148,300