Visualizing the effect of CDKL5 deficiency on ciliary core structures

CDKL5CDKL5 Pilot Grant Programme
Written by Million Dollar Bike Ride

Awardee: Alan Brown, PhD

Institution: Harvard Medical School

Award Amount: $150,000

Million Dollar Bike Ride
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Elucidate the neural mechanisms underlying sleep disturbances and the relation between seizures and sleep-wake cycle in CDKL5 deficiency disorder (CDD)
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Incorporation of functional unnatural amino acids into CDKL5 to study its function in cells