Elucidate the neural mechanisms underlying sleep disturbances and the relation between seizures and sleep-wake cycle in CDKL5 deficiency disorder (CDD)

Awardee: Liqin Cao, PhD

Institution: Tsukuba University

Award Amount: $139,940

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Characterization and correction of Cdkl5 nuclear function in human CDD neurons during maturation

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Visualizing the effect of CDKL5 deficiency on ciliary core structures