Mechanistic study of WDR45/45B and their binding partner ATG2 in the autophagy pathway of neural cells

Awardee: Hong Zhang

Institution: University of Massachusetts Medical School

Award Amount: $51,020

Funding Period: February 1, 2019 - January 31, 2020

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The use of a patient-centric neuronal cell model of Beta-Propeller Protein-Associated Neurodegeneration (BPAN) as a platform to develop novel therapies

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Biomarker correlates of neurocognitive outcomes in the cerebrospinal fluid in MPS I