MEK inhibition for RASopathy associated hypertrophic cardiomyopathy
Awardee: Gregor Andelfinger
Institution: CHU Sainte Justine Research Center, Université de Montréal
Award Amount: $59,220
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Structural/functional characterization of full-length hCDKL5 isoform 1 produced in recombinant marine bacteria and use of pharmacological chaperones to stabilize hCDKL5 missense mutants
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